https://scholars.lib.ntu.edu.tw/handle/123456789/581551
標題: | Synthesis, bifunctionalization, and remarkable adsorption performance of benzene-bridged periodic mesoporous organosilicas functionalized with high loadings of carboxylic acids | 作者: | Wu H.-Y Shieh F.-K Kao H.-M Chen Y.-W Deka J.R Liao S.-H Wu K.C.-W. KEVIN CHIA-WEN WU |
關鍵字: | Biomedical applications; Doxorubicin; High adsorption capacity; Methylene Blue; Periodic mesoporous organosilicas; Periodic mesoporous organosilicas (PMOs); Powder X ray diffraction; Solid-state NMR spectroscopy; Adsorption; Aromatic compounds; Benzene; Drug delivery; Medical applications; Mesoporous materials; Nuclear magnetic resonance spectroscopy; Oligomers; Silica; X ray diffraction; Carboxylic acids; benzene derivative; carboxylic acid; doxorubicin; methylene blue; organosilicon derivative; adsorption; article; chemical model; chemistry; drug delivery system; nuclear magnetic resonance spectroscopy; porosity; synthesis; X ray diffraction; Adsorption; Benzene Derivatives; Carboxylic Acids; Doxorubicin; Drug Delivery Systems; Magnetic Resonance Spectroscopy; Methylene Blue; Models, Chemical; Organosilicon Compounds; Porosity; X-Ray Diffraction | 公開日期: | 2013 | 卷: | 19 | 期: | 20 | 起(迄)頁: | 6358-6367 | 來源出版物: | Chemistry - A European Journal | 摘要: | Highly ordered benzene-bridged periodic mesoporous organosilicas (PMOs) that were functionalized with exceptionally high loadings of carboxylic acid groups (COOH), up to 80 mol % based on silica, have been synthesized and their use as adsorbents for the adsorption of methylene blue (MB), a basic dye pollutant, and for the loading and release of doxorubicin (DOX), an anticancer drug, is demonstrated. These COOH-functionalized benzene-silicas were synthesized by the co-condensation of 1,4-bis(triethoxysilyl) benzene (BTEB) and carboxyethylsilanetriol sodium salt (CES), an organosilane that contained a carboxylic acid group, in the presence of non-ionic oligomeric surfactant Brij 76 in acidic medium. The materials thus obtained were characterized by a variety of techniques, including powder X-ray diffraction (XRD), nitrogen-adsorption/ desorption isotherms, TEM, and 13C and 29Si solid-state NMR spectroscopy. Owing to the exceptionally high loadings of COOH groups, their high surface areas, and possible π-π-stacking interactions, these adsorbents have very high adsorption capacities and extremely rapid adsorption rates for MB removal and for the controlled loading/release of DOX, thus manifesting their great potential for environmental and biomedical applications. Copyright ? 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84877295512&doi=10.1002%2fchem.201204400&partnerID=40&md5=cb7db9e398c1e6df3ae7ca371d88a6d9 https://scholars.lib.ntu.edu.tw/handle/123456789/581551 |
ISSN: | 09476539 | DOI: | 10.1002/chem.201204400 |
顯示於: | 化學工程學系 |
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