Different clinical and genetic features of Alagille patients with progressive disease versus a jaundice-free course
Journal
JGH open : an open access journal of gastroenterology and hepatology
Journal Volume
6
Journal Issue
12
Pages
839
Date Issued
2022-12
Author(s)
Chiang, Che-Ming
Lai, Ming-Wei
Li, Huei-Ying
Liou, Bang-Yu
Abstract
Alagille syndrome (ALGS) is a multisystem disorder with variable clinical courses. This study investigated the clinical and genetic features of ALGS patients with different outcomes and analyzed the liver pathology at liver transplantation (LT) compared with that in biliary atresia (BA).
Subjects
Alagille syndrome; JAG1 gene; biliary atresia; jaundice free; liver transplantation
Publisher
WILEY
Type
journal article