Systolic blood pressure as the mediator of the effect of early menarche on the risk of coronary artery disease: A Mendelian randomization study
Journal
Frontiers in cardiovascular medicine
Journal Volume
9
Date Issued
2023-01
Author(s)
Fan, Hsien-Yu
Huang, Yen-Tsung
Chen, Yun-Yu
Hsu, Justin BoKai
Chen, Yang-Ching
Abstract
Menarche timing may not be directly associated with the risk of coronary artery disease (CAD). Therefore, we investigated the roles of metabolic factors in explaining the effect of age at menarche on CAD risk.
Subjects
Mendelian randomization; cardiovascular disease; mediator; menarche age; metabolic factor
SDGs
Publisher
FRONTIERS MEDIA SA
Type
journal article