Disseminated Nocardia farcinica infection in a uraemia patient with idiopathic thrombocytopenia purpura receiving steroid therapy
Journal
Journal of Medical Microbiology
Journal Volume
54
Journal Issue
11
Pages
1107-1110
Date Issued
2005
Author(s)
Abstract
Nocardia farcinica has been reported as an increasingly frequent cause of localized and disseminated infections in immunocompromised patients in recent years, but N. farcinica bacteraemia remains a rare finding. Here, the case is described of a 68-year-old man with end-stage renal disease and idiopathic thrombocytopenia purpura treated with steroid therapy who developed disseminated infection (bacteraemia, multilobar pneumonia and brain abscesses) due to N. farcinica. The isolate was confirmed by partial sequencing analysis of the 16S rRNA gene. The patient recovered after prolonged trimethoprim-sulfamethoxazole therapy with no recurrence in over 1 year. ? 2005 SGM.
SDGs
Other Subjects
amikacin; amoxicillin plus clavulanic acid; ampicillin; cefotaxime; ciprofloxacin; cotrimoxazole; gentamicin; prednisolone; RNA 16S; steroid; sultamicillin; aged; article; bacteremia; bacterium isolate; bacterium isolation; brain abscess; case report; chill; clinical feature; convalescence; coughing; fever; gene sequence; headache; human; idiopathic thrombocytopenic purpura; immune deficiency; kidney failure; long term care; male; Nocardia farcinica; nocardiosis; nucleotide sequence; pneumonia; priority journal; sequence analysis; steroid therapy; symptom; uremia; Aged; Bacteremia; Brain Abscess; DNA, Bacterial; DNA, Ribosomal; Humans; Male; Nocardia; Nocardia Infections; Pneumonia; Purpura, Thrombocytopenic, Idiopathic; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Steroids; Trimethoprim-Sulfamethoxazole Combination; Uremia
Type
journal article