https://scholars.lib.ntu.edu.tw/handle/123456789/186691
標題: | Suppression of the Hypothalamus-Pituitary Somatotrope Axis in Men with Spinal Cord Injuries 男性脊髓損傷患者之下視丘─腦垂體生長激素細胞軸受抑 制 |
作者: | HUANG, TIEN-SHANG WANG, YEN-HO LIEN, I-NAN 黃天祥 王顏和 連倚南 |
公開日期: | 1995 | 卷: | v.44 | 期: | n.9 | 起(迄)頁: | 1116-1120 | 來源出版物: | Metabolism | 摘要: | Thirty-two men with spinal cord injury(SCI) were studied for evaluation of the hypothalamus-pituitary somatotrope axis, using growth hormone-(GH)-releasing hormone(GHRH) and insulin-induced hypoglycemia. Twenty- six age-matched normal male volunteers served as controls. Six SCI subjects (18.7%) had elevated basal follicle- stimulating hormone (FSH) levels, eight (25.0%) had hyperprolactinemia, and 11(34.4%) had reduced serum insulin -like growth factor-1 (IGF-1) levels. Twenty SCI subjects(62 .5%) had reduced and/or delayed GH responses to GHRH, and eight (25.8%) had reduced GH response to insulin-induced hypoglycemia. Seven of eight hyperprolactinemic SCI subjects showed reduced GH response to GHRH and /or insulin-induced hypoglycemia. These findings are consistent with the notion that SCI subjects have a reduced central dopaminergic tone. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/99571 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。