https://scholars.lib.ntu.edu.tw/handle/123456789/194416
標題: | 兒童初發性幽門螺旋桿菌感染 | 作者: | 倪衍玄 | 關鍵字: | Helicobacter pylori;urease;13C-urea breath test;stool antigen test;serology | 公開日期: | 2000 | 出版社: | 臺北市:國立臺灣大學醫學院小兒科 | 摘要: | Helicobacter pylori (H. pylori) infection has been associated with gastritis, peptic ulcer, and gastric malignancy. Invasive and noninvasive tests have been developed for the diagnosis of H. pylori infection. Since H. pylori infection is mostly acquired in childhood and adolescence, accurate diagnosis of the infection in the pediatric population is important. The noninvasive diagnostic methods are particularly feasible in children. We conducted a study to compare the invasive tests: culture, biopsy urease test (BUT), histology, and polymerase chain reaction (PCR) on gastric biopsy specimens, with noninvasive tests: serology, 13C-urea breath test (13C-UBT), and a new diagnostic modality: stool antigen test to diagnose H. pylori infection in children. A total of 53 symptomatic children were enrolled into this study and all had completed the seven diagnostic tests for H. pylori. Our results showed all the diagnostic tests except serology were excellent methods of diagnosing H. pylori infection in children. The diagnostic accuracy of the seven tests were as follows: stool antigen test 96.2%; BUT 96.2%; histology 98.1%; PCR 94.3%; culture 98.1%; 13CUBT 100%; and serology 84.9%. Stool antigen test, being highly sensitive and specific as shown in our data, will be potentially very helpful in diagnosing H. pylori infection in children. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/22851 | 其他識別: | 892314B002142 | Rights: | 國立臺灣大學醫學院小兒科 |
顯示於: | 醫學系 |
檔案 | 描述 | 大小 | 格式 | |
---|---|---|---|---|
892314B002142.pdf | 57.88 kB | Adobe PDF | 檢視/開啟 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。