https://scholars.lib.ntu.edu.tw/handle/123456789/194950
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 小兒科 | en |
dc.contributor.author | LEE, PING-ING | en |
dc.creator | 李秉穎 | zh-tw |
dc.creator | LEE, PING-ING | en |
dc.date | 2002 | en |
dc.date.accessioned | 2008-12-29T06:13:51Z | - |
dc.date.accessioned | 2018-07-11T17:55:26Z | - |
dc.date.available | 2008-12-29T06:13:51Z | - |
dc.date.available | 2018-07-11T17:55:26Z | - |
dc.date.issued | 2002 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/94842 | - |
dc.description.abstract | Objective: From October 1996 to March 1997, a cluster of II cases of neonatal sepsis caused by Enterobacter cloacae with similar antimicrobial susceptibility patterns occurred in a neonatal intensive care unit. This outbreak prompted an investigation. Method: Twelve isolates obtained from 6 neonatal patients who developed E cloacae sepsis during the outbreak were analyzed. Four E cloacae isolates from 2 preterm neonates without E cloacae infection on the same ward, and I isolate from the hands of a nurse, were also examined. No E cloacae were isolated from the environment . Bacterial DNA digested with XbaI or NotI was analyzed with pulsed-field gel electrophoresis. Result: Three distinct banding patterns were identified by pulsed-field gel electrophoresis. Of the 6 preterm infants with sepsis, strain I was identified in I, strain II in 2, a mixed infection of strains I and II in 2, and strain III was found in only I infant. An isolate from the hands of a nurse was identified as strain II, as were the 4 isolates from the 2 preterm neonates without E cloacae infection. Thus, this outbreak of sepsis was caused by 2 genotypes of E cloacae. Conclusion: This study demonstrates that pulsed-field gel electrophoresis with restriction enzyme digestion is a valuable tool for genetic characterization of multidrug- resistant E cloacae strains during outbreaks. | en |
dc.language | en-us | en |
dc.language.iso | en_US | - |
dc.relation | AMERICAN JOURNAL OF INFECTION CONTROL v.30 n.7 pp.381-385 | en |
dc.relation.ispartof | AMERICAN JOURNAL OF INFECTION CONTROL | - |
dc.subject | GENOMIC RESTRICTION FRAGMENTS | en |
dc.subject | NOSOCOMIAL ENTEROBACTER | en |
dc.subject | DNA | en |
dc.subject | INFECTION | en |
dc.title | Study of an Outbreak of Enterobacter Cloacae Sepsis in a Neonatal Intensive Care Unit: The Application of Epidemiologic Chromosome Profiling by Pulsed-Field Gel Electrophoresis | en |
dc.type | journal article | en |
dc.relation.pages | 381-385 | - |
dc.relation.journalvolume | v.30 | - |
dc.relation.journalissue | n.7 | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en_US | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
顯示於: | 醫學系 |
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