https://scholars.lib.ntu.edu.tw/handle/123456789/202002
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor | 檢驗醫學科 | en |
dc.contributor.author | DAI, DAO-FU | en_US |
dc.contributor.author | FU-TIEN CHIANG | en_US |
dc.contributor.author | JIUNN-LEE LIN | en_US |
dc.contributor.author | CHI-LING CHEN | en_US |
dc.contributor.author | CHANG, CHEE-JEN | en_US |
dc.contributor.author | LING-PING LAI | en_US |
dc.contributor.author | HSU, KWAN-LIH | en_US |
dc.contributor.author | TSENG, CHUEN-DEN | en_US |
dc.contributor.author | TSENG, YUNG-ZU | en_US |
dc.contributor.author | JUEY-JEN HWANG | en_US |
dc.creator | 戴道福;江福田;林俊立;陳祈玲;張啟仁;賴凌平;許寬立;曾春典;曾淵如;黃瑞仁 | zh-tw |
dc.creator | DAI, DAO-FU;CHIANG, FU-TIEN;LIN, JIUNN-LEE;CHEN, CHI-LING;CHANG, CHEE-JEN;LAI, LING-PING;HSU, KWAN-LIH;TSENG, CHUEN-DEN;TSENG, YUNG-ZU;HWANG, JUEY-JEN | en |
dc.date | 2007 | en |
dc.date.accessioned | 2008-12-08T02:28:06Z | - |
dc.date.accessioned | 2018-07-12T09:04:23Z | - |
dc.date.available | 2008-12-08T02:28:06Z | - |
dc.date.available | 2018-07-12T09:04:23Z | - |
dc.date.issued | 2007-05 | - |
dc.identifier.issn | 09296646 | - |
dc.identifier.uri | http://ntur.lib.ntu.edu.tw//handle/246246/89450 | - |
dc.identifier.uri | https://www.scopus.com/record/display.uri?eid=2-s2.0-34250616292&doi=10.1016%2fS0929-6646%2809%2960319-3&origin=inward&txGid=be3296dc06621f260f1544c05b2a9afe | - |
dc.description.abstract | Background/Purpose: Elevation of C-reactive protein (CRP) level is associated with increased risk of cardiovascular events. The 1059 G > C polymorphism in exon 2 of the CRP gene has been shown to affect plasma concentration of CRP. We want to elucidate the effect of this polymorphism on the development of coronary artery disease (CAD) among the Chinese population in Taiwan. Methods: We scrutinized 536 patients undergoing coronary angiography (365 patients with CAD and 171 controls with patent coronaries) and evaluated the association of CRP gene 1059 G > C polymorphism with CAD. Genotyping of the polymorphism was performed by polymerase chain reaction and MaeIII restriction enzyme digestion. Results: The CC genotype was associated with lower plasma CRP concentration (GG, 6.5±5.8, GC, 3.3 ± 4.4; CC, 2.3±3.1 mg/L; p= 0.02). Subjects with CAD or myocardial infarction (MI) had significantly higher plasma CRP concentration than that in controls (CAD vs. controls, 8.9±18.9 vs. 3.3±7.2 mg/L; p<0.001), while patients with MI showed higher CRP when compared to those with chronic stable angina (13.5 ±22.9 vs. 5.2±14.1 mg/L; p [removed]C polymorphism is associated with plasma CRP concentration among Chinese in Taiwan receiving coronary angiography. © 2007 Elsevier & Formosan Medical Association. | en_US |
dc.language | en-us | en |
dc.language.iso | en_US | en_US |
dc.relation | JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION v.106 n.5 pp.347-354 | en_US |
dc.relation.ispartof | JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION | en_US |
dc.subject | C-reactive protein | en_US |
dc.subject | CRP | en_US |
dc.subject | coronary artery disease | en_US |
dc.subject | genetic polymorphism | en_US |
dc.subject | myocardial infarction | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.title | Human C-Reactive Protein (Crp) Gene 1059 G>C Polymorphism Is Associated with Plasma Crp Concentration in Patients Receiving Coronary Angiography | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/S0929-6646(09)60319-3 | - |
dc.identifier.pmid | 17561469 | - |
dc.relation.pages | 347 | en_US |
dc.relation.journalvolume | 106 | en_US |
dc.relation.journalissue | 5 | en_US |
dc.relation.pageend | 354 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en_US | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Clinical Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.orcid | 0000-0003-4936-8968 | - |
crisitem.author.orcid | 0000-0003-2148-3956 | - |
crisitem.author.orcid | 0000-0002-9651-7420 | - |
crisitem.author.orcid | 0000-0001-6437-0455 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
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