https://scholars.lib.ntu.edu.tw/handle/123456789/202429
Title: | Changes in Macrolide Resistance among Respiratory Pathogens after Decreased Erythromycin Consumption in Taiwan | Authors: | HSUEH, PO-REN SHYR, JAINN-MING WU, JIUNN-JONG |
Keywords: | Anti-Bacterial Agents/ pharmacology;Azithromycin/ pharmacology;Bacterial Infections/drug therapy;Comparative Study;Drug Resistance, Bacterial;Drug Utilization | Issue Date: | 2006 | Journal Volume: | v.12 | Journal Issue: | n.3 | Start page/Pages: | 296-298 | Source: | CLINICAL MICROBIOLOGY AND INFECTION | Abstract: | Measures to alleviate the growing problem of macrolide resistance in Taiwan resulted in a decrease in macrolide consumption, from 0.629 defined daily doses/1000 inhabitants per day (DIDs) in 1999 to 0.301 DIDs in 2003 (a reduction of 52%). A linear relationship was observed between the decline in erythromycin consumption and the decline in erythromycin resistance in Streptococcus pyogenes (46% in 1999 vs. 17% in 2003; p < 0. 001) and azithromycin resistance in Haemophilus influenzae (31% in 2000 vs . 0% in 2003; p < 0.001). However, the rate of erythromycin resistance in Streptococcus pneumoniae showed a continued increase, from 80.2% in 1999 to 92% in 2003. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/94637 |
Appears in Collections: | 醫學系 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.