https://scholars.lib.ntu.edu.tw/handle/123456789/291590
Title: | New constituents and antiplatelet aggregation and anti-HIV principles of Artemisia capillaris | Authors: | CHE-MING TENG | Issue Date: | 2001 | Journal Volume: | 9 | Journal Issue: | 1 | Start page/Pages: | 77-83 | Source: | Bioorganic and Medicinal Chemistry | Abstract: | Five new constituents including a flavonoid, artemisidin A (1), and four coumarins, artemicapins A (2), B (3), C (4) and D (5), together with 70 known compounds (6-75), have been isolated and characterized from the aerial part of Artemisia capillaris. The structures of these compounds were determined from spectral analyses and/or chemical evidence. Among them, 15 compounds (3, 6, 10, 18, 30-32, 38-41, 44, 45, 51, and 55) showed antiplatelet aggregation activity and three compounds (10, 17, and 51) demonstrated significant activity against HIV replication in H9 lymphocytic cells. ? 2000 Elsevier Science Ltd. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0035183932&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/291590 |
DOI: | 10.1016/S0968-0896(00)00225-X | SDG/Keyword: | artemicapin A; artemicapin B; artemicapin C; artemicapin D; Artemisia capillaris extract; artemisidin A; coumarin derivative; flavonoid; unclassified drug; animal cell; antiviral activity; article; controlled study; drug isolation; drug structure; Human immunodeficiency virus; lymphocyte; nonhuman; thrombocyte aggregation inhibition; virus inhibition; virus replication; Acetylene; Animals; Anti-HIV Agents; Artemisia; Blood Platelets; Caffeic Acids; Coumarins; Magnetic Resonance Spectroscopy; Molecular Structure; Plants, Medicinal; Platelet Aggregation Inhibitors; Rabbits; Spectrophotometry; Artemisia capillaris |
Appears in Collections: | 醫學系 |
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