https://scholars.lib.ntu.edu.tw/handle/123456789/298580
Title: | Antitumor activity of milk kefir and soy milk kefir in tumor-bearing mice | Authors: | JE-RUEI LIU | Issue Date: | 2002 | Journal Volume: | 44 | Journal Issue: | 2 | Start page/Pages: | 182-187 | Source: | Nutrition and Cancer | Abstract: | The effects of oral administration of milk and soy milk kefirs on tumor growth in tumor-bearing mice and the mucosal immunoglobulin A response in mice were studied. Oral administration of milk and soy milk kefirs to mice inoculated with sarcoma 180 tumor cells resulted in 64.8% and 70.9% inhibition of tumor growth, respectively, compared with controls. In addition, oral administration of the two kefir types induced apoptotic tumor cell lysis. Total immunoglobulin A levels for tissue extracts from the wall of the small intestine were also significantly higher for mice fed a milk kefir or a soy milk kefir regimen for 30 days. These results suggest that milk and soy milk kefirs may be considered among the more promising food components in terms of cancer prevention and enhancement of mucosal resistance to gastrointestinal infection. |
URI: | http://www.scopus.com/inward/record.url?eid=2-s2.0-0038439628&partnerID=MN8TOARS http://scholars.lib.ntu.edu.tw/handle/123456789/298580 |
SDG/Keyword: | genistein; immunoglobulin A; milk kefir; milk protein; soy milk kefir; unclassified drug; antineoplastic agent; immunoglobulin A; animal experiment; animal model; apoptosis; article; body weight; cancer graft; cancer inhibition; controlled study; female; fermentation; gastrointestinal infection; histopathology; immunoglobulin production; lactic acid bacterium; mouse; mucosal immunity; nonhuman; sarcoma cell; tumor cell destruction; tumor volume; animal; dairy product; disease model; drug effect; drug screening; gastrointestinal tumor; immunology; Institute for Cancer Research mouse; mucosa; Peyer patch; sarcoma; soybean; statistics; Animalia; Bacteria (microorganisms); Animals; Antineoplastic Agents; Body Weight; Cultured Milk Products; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Gastrointestinal Neoplasms; Immunoglobulin A; Mice; Mice, Inbred ICR; Mucous Membrane; Peyer's Patches; Sarcoma, Experimental; Soybeans |
Appears in Collections: | 生物科技研究所 |
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