|Title:||A simple formula useful for positional cloning||Authors:||Richard T. Durrett
Steven D. Tanksley
|Issue Date:||2002||Journal Volume:||160||Start page/Pages:||353-355||Source:||Genetics||Abstract:||
We derive a formula for the distribution of the length T of the recombination interval containing a target gene and using N gametes in a region where R kilobases correspond to 1 cM. The formula can be used to calculate the number of meiotic events required to narrow a target gene down to a specific interval size and hence should be useful for planning positional cloning experiments. The predictions of this formula agree well with the results from a number of published experiments in Arabidopsis.
|Appears in Collections:||農藝學系|
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