https://scholars.lib.ntu.edu.tw/handle/123456789/405951
標題: | A dual signal amplification nanosensor based on SERS technology for detection of tumor-related DNA | 作者: | Lin, D. Gong, T. Qiu, S. Wu, Q. Tseng, C.-Y. Kong, K.V. Chen, G. Chen, R. |
公開日期: | 2019 | 卷: | 55 | 期: | 11 | 起(迄)頁: | 1548-1551 | 來源出版物: | Chemical Communications | 摘要: | A dual signal amplification method based on surface-enhanced Raman scattering (SERS) is developed by photo-triggered release of SERS probes from mesoporous silica-coated Au nanorods (SiO2@Au) and the use of a specially-designed SERS substrate with an internal reference. Two metal carbonyl (metal-CO) labels (Os-SCO and Re-SCO) are proposed here as novel interference-free labels. Results demonstrate that tumor-related DNA can be quantitatively detected by this reliable and ultra-sensitive SERS platform. ? 2019 The Royal Society of Chemistry. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060914798&doi=10.1039%2fc8cc07461e&partnerID=40&md5=617792dd63c5c9c65a0425135f3f6174 https://scholars.lib.ntu.edu.tw/handle/123456789/405951 |
DOI: | 10.1039/c8cc07461e | SDG/關鍵字: | carbonyl derivative; circulating tumor DNA; gold nanorod; mesoporous silica nanoparticle; coordination compound; DNA; gold; nanotube; osmium; rhenium; silicon dioxide; Article; branched DNA signal amplification assay; cancer diagnosis; controlled study; nasopharynx cancer; quantitative analysis; standard; surface enhanced Raman spectroscopy; chemistry; genetics; human; laser; metabolism; neoplasm; pathology; Raman spectrometry; Coordination Complexes; DNA, Neoplasm; Gold; Humans; Lasers; Nanotubes; Neoplasms; Osmium; Rhenium; Silicon Dioxide; Spectrum Analysis, Raman |
顯示於: | 化學系 |
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