|Title:||Preparation of polylactide scaffolds||Authors:||Ho M.-H.
|Issue Date:||2009||Start page/Pages:||117-130||Source:||Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications||Abstract:||
Porous polymers with suitable porous structures and chemical properties can serve as templates to guide cells to differentiate and grow into tissues or even organs. Such biomedical applications have drawn a lot of research attention and forms a research eld called tissue engineering. For an application in tissue engineering, the polymer should have appropriate biocompatibility and biodegradability. In addition, high porosity, a large surface area, a suitable pore size, and a highly interconnected pore structure are also needed. In this chapter, we concentrate on giving an overview of the methods for preparing a three-dimensional porous polymer structure. Polylactide (PLA), an Food and Drug Administration (FDA)-approved biodegradable polymer for clinical use, is used as an example polymer to demonstrate the pore-forming techniques. First, brief introductions to tissue engineering and PLA are given. An overview of the techniques to fabricate porous PLA then follows. ? 2009 by Taylor & Francis Group, LLC.
|Appears in Collections:||化學工程學系|
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