One-step rapid fabrication of paper-based microfluidic devices using fluorocarbon plasma polymerization
Journal
Microfluidics and Nanofluidics
Journal Volume
16
Journal Issue
5
Pages
811-818
Date Issued
2014
Author(s)
Kao P.-K.
Abstract
In this work, we demonstrated an all-dry, top-down, and one-step rapid process to fabricate paper-based microfluidic devices using fluorocarbon plasma polymerization. This process is able to create fluorocarbon-coated hydrophobic patterns on filter paper substrates while maintaining the trench and detection regions intact and free of contamination after the fabrication process, as confirmed by attenuated total reflectance-Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. We have shown that the processing time is one critical factor that influences the device performance. For the device fabricated with a sufficiently long processing time (180 s), the sample fluid flow can be well confined in the patterned trenches. By testing the device with an 800 £gm channel width, a sample solution amount as small as 4.5 £gL is sufficient to perform the test. NO2 - assay is also performed and shows that such a device is capable for biochemical analysis. ? 2014 Springer-Verlag Berlin Heidelberg.
Type
journal article