Photo-crosslinked keratin/chitosan membranes as potential wound dressing materials
Journal
Polymers
Journal Volume
10
Journal Issue
9
Date Issued
2018
Author(s)
Abstract
In this study, we combined two kinds of natural polymers, chitosan and keratin, to develop a portable composite membrane via UV irradiation. UV-crosslinking without an additional chemical agent makes the fabrication more ideal by reducing reactants and avoiding residual toxic chemicals. This novel composite could perform synergistic functions benefitting from chitosan and keratin; including a strong mechanical strength, biodegradability, biocompatibility, better cell adhesion, and proliferation characteristics. Furthermore, compared with our previous research, this keratin-chitosan composite membrane was improved in that it was made to be portable, enabling it to be versatile and have various applications in vitro and in vivo. Based on these facts, this innovative composite membrane has high potential for serving as an outstanding candidate for wound healing or other biomedical applications. ? 2018 by the authors.
Subjects
Chitosan
Composite membrane
Keratin
UV-crosslink
SDGs
Other Subjects
Biocompatibility; Biodegradability; Cell adhesion; Chitosan; Composite membranes; Crosslinking; Indicators (chemical); Irradiation; Keratin; Medical applications; Biomedical applications; Chemical agent; Chitosan composites; High potential; Toxic chemicals; UV irradiation; UV-crosslinking; Wound dressing materials; Membranes
Type
journal article