https://scholars.lib.ntu.edu.tw/handle/123456789/410328
標題: | Photo-crosslinked keratin/chitosan membranes as potential wound dressing materials | 作者: | Lin C.-W. Chen Y.-K. Lu M. KUO-LONG LOU Yu J. |
關鍵字: | Chitosan;Composite membrane;Keratin;UV-crosslink | 公開日期: | 2018 | 卷: | 10 | 期: | 9 | 來源出版物: | Polymers | 摘要: | In this study, we combined two kinds of natural polymers, chitosan and keratin, to develop a portable composite membrane via UV irradiation. UV-crosslinking without an additional chemical agent makes the fabrication more ideal by reducing reactants and avoiding residual toxic chemicals. This novel composite could perform synergistic functions benefitting from chitosan and keratin; including a strong mechanical strength, biodegradability, biocompatibility, better cell adhesion, and proliferation characteristics. Furthermore, compared with our previous research, this keratin-chitosan composite membrane was improved in that it was made to be portable, enabling it to be versatile and have various applications in vitro and in vivo. Based on these facts, this innovative composite membrane has high potential for serving as an outstanding candidate for wound healing or other biomedical applications. ? 2018 by the authors. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/410328 | ISSN: | 20734360 | DOI: | 10.3390/polym10090987 | SDG/關鍵字: | Biocompatibility; Biodegradability; Cell adhesion; Chitosan; Composite membranes; Crosslinking; Indicators (chemical); Irradiation; Keratin; Medical applications; Biomedical applications; Chemical agent; Chitosan composites; High potential; Toxic chemicals; UV irradiation; UV-crosslinking; Wound dressing materials; Membranes |
顯示於: | 化學工程學系 |
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