https://scholars.lib.ntu.edu.tw/handle/123456789/411228
標題: | New cembranoids and a biscembranoid peroxide from the soft coral sarcophyton cherbonnieri | 作者: | Peng, Chia Chi Huang, Chiung Yao Ahmed, Atallah F. Hwang, Tsong Long CHANG-FENG DAI Sheu, Jyh Horng |
關鍵字: | Anti-inflammatory activity | Biscembranoid peroxide | Cembranoid | Elastase release inhibition | Sarcophyton cherbonnieri | 公開日期: | 1-一月-2018 | 出版社: | MDPI | 卷: | 16 | 期: | 8 | 來源出版物: | Marine Drugs | 摘要: | © 2018 IAEME Publication. All rights reserved. Six new cembranoids, cherbonolides A−E (1-5) and bischerbolide peroxide (6), along with one known cembranoid, isosarcophine (7), were isolated from the Formosan soft coral Sarcophyton cherbonnieri. The structures of these compounds were elucidated by detailed spectroscopic analysis and chemical methods. Compound 6 was discovered to be the first example of a molecular skeleton formed from two cembranoids connected by a peroxide group. Compounds 1-7 were shown to have the ability of inhibiting the production of superoxide anions and elastase release in N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLF/CB)-induced human neutrophils. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/411228 | ISSN: | 1660-3397 | DOI: | 10.3390/md16080276 |
顯示於: | 海洋研究所 |
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