anamiR: integrated analysis of MicroRNA and gene expression profiling
Journal
BMC bioinformatics
Journal Volume
20
Journal Issue
1
Date Issued
2019-05-14
Author(s)
Abstract
With advancements in high-throughput technologies, the cost of obtaining expression profiles of both mRNA and microRNA in the same individual has substantially decreased. Integrated analysis of these profiles can help to elucidate the functional effects of RNA expression in complex diseases, such as cancer. However, fundamental discrepancies are observed in the results from microRNA-mRNA target gene prediction algorithms, and few packages can be used to analyze microRNA and mRNA expression levels simultaneously.
Subjects
Functional enrichment analysis; Gene expression; MicroRNA; R/Bioconductor
SDGs
Other Subjects
Nucleic acids; RNA; Biological functions; Functional enrichment analysis; Gene expression profiling; High throughput technology; Microarray data sets; MicroRNAs; MRNA expression level; R/Bioconductor; Gene expression; microRNA; algorithm; gene expression profiling; genetics; human; procedures; Algorithms; Gene Expression Profiling; Humans; MicroRNAs
Publisher
BMC
Type
journal article