https://scholars.lib.ntu.edu.tw/handle/123456789/412845| Title: | anamiR: integrated analysis of MicroRNA and gene expression profiling | Authors: | Wang, Ti-Tai Lee, Chien-Yueh LIANG-CHUAN LAI MONG-HSUN TSAI TZU-PIN LU Chuang, Eric Y |
Keywords: | Functional enrichment analysis; Gene expression; MicroRNA; R/Bioconductor | Issue Date: | 14-May-2019 | Publisher: | BMC | Journal Volume: | 20 | Journal Issue: | 1 | Source: | BMC bioinformatics | Abstract: | With advancements in high-throughput technologies, the cost of obtaining expression profiles of both mRNA and microRNA in the same individual has substantially decreased. Integrated analysis of these profiles can help to elucidate the functional effects of RNA expression in complex diseases, such as cancer. However, fundamental discrepancies are observed in the results from microRNA-mRNA target gene prediction algorithms, and few packages can be used to analyze microRNA and mRNA expression levels simultaneously. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/412845 | ISSN: | 1471-2105 | DOI: | https://api.elsevier.com/content/abstract/scopus_id/85065705024 10.1186/s12859-019-2870-x |
| Appears in Collections: | 流行病學與預防醫學研究所 |
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