https://scholars.lib.ntu.edu.tw/handle/123456789/413300
標題: | Glucosinolates fortification of cruciferous sprouts by sulphur supplementation during cultivation to enhance anti-cancer activity | 作者: | Kestwal R.M. Lin J.C. Bagal-Kestwal D. Chiang B.H. |
關鍵字: | Anti-cancer;Cruciferous sprouts;CT26;Glucosinolates;HepG2;Sulphur | 公開日期: | 2011 | 卷: | 126 | 期: | 3 | 起(迄)頁: | 1164-1171 | 來源出版物: | Food Chemistry | 摘要: | The cruciferous sprouts, including cabbage (Brassica oleracea), broccoli (Brassica capitata) and radish (Raphanus sativus), were cultivated with supplementation of sulphur salts. With supplementation of sulphur at 60 kg/ha, a 2-5-fold increases in total glucosinolates contents in the sprouts were observed. The individual glucosinolates whose concentration increased most significantly, included progoitrin, glucoerucin, glucobrassicin, glucohirsutin and 4-methoxybrassicin. The antioxidant properties of these sulphur supplemented sprouts were also higher than that of the normal sprouts due to the increases of phenolic compounds. Consequently, the glucosinolates fortified sprouts had higher anti-proliferative activity against HepG2 human hepatocarcinoma cells than the normal sprouts, as the cell viability decreased by 22-35%. Also in CT26 mouse colorectal cancer cells, the cell viability decrease by 34-59%. ? 2010 Elsevier Ltd. All rights reserved. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/413300 | ISSN: | 03088146 | DOI: | 10.1016/j.foodchem.2010.11.152 | SDG/關鍵字: | Anti-cancer; Cruciferous sprouts; CT26; Glucosinolates; HepG2; Sulphur; Phenols; Sulfur; phenol; sulfur; animal cell; antineoplastic activity; article; broccoli; cabbage; cancer cell; cell strain HepG2; cell viability; colorectal cancer; human; human cell; mouse; nonhuman; radish; sprout; Brassica capitata; Brassica oleracea; Brassica oleracea var. capitata; Brassica oleracea var. italica; Raphanus sativus |
顯示於: | 食品科技研究所 |
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