SHP-1 (PTPN6) keeps the inflammation at bay: limiting IL-1α-mediated neutrophilic dermatoses by preventing Syk kinase activation
Journal
Cellular & molecular immunology
Journal Volume
14
Journal Issue
11
Pages
881
Date Issued
2017-07-10
Author(s)
You, Ren-In
SDGs
Other Subjects
autoantibody; caspase 8; Fas associated death domain protein; interleukin 1alpha; interleukin 1beta converting enzyme; membrane protein; myeloid differentiation factor 88; phosphatidylinositol 4 phosphate kinase; protein kinase Syk; protein tyrosine phosphatase SHP 1; receptor interacting protein kinase 1; unclassified drug; acute febrile neutrophilic dermatosis; autoinflammatory disease; biosynthesis; bone marrow cell; cell viability; disease course; fibroblast; human; immune response; immunomodulation; innate immunity; missense mutation; nonhuman; Note; oxidative stress; protein analysis; protein degradation; protein function; protein phosphorylation; protein protein interaction; protein secretion; signal transduction
Publisher
CHIN SOCIETY IMMUNOLOGY
Type
journal article