A comprehensive characterization of aggravated aging-related changes in T lymphocytes and monocytes in end-stage renal disease: the iESRD study
Journal
Immunity & ageing : I & A
Journal Volume
15
Journal Issue
1
Date Issued
2018
Author(s)
Chiu, Yen-Ling
Shu, Kai-Hsiang
Chou, Tzu-Ying
Lay, Fang-Yun
Lin, Cheng-Jui
Litjens, Nicolle H R
Betjes, Michiel G H
Bermudez, Selma
Kao, Kung-Chi
Wang, George
Peng, Yu-Sen
Chuang, Yi-Fang
Abstract
Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of the immune system. Nevertheless, the etiology and impact of these changes in ESRD patients remain unknown.
Subjects
Aging; CVD; ESRD; Immunosenescence; Inflammation
SDGs
Other Subjects
indican; para cresyl sulfate; unclassified drug; uremic toxin; adaptive immunity; adult; aging; Article; cardiovascular disease; CD4 lymphocyte count; CD4+ T lymphocyte; CD8 lymphocyte count; CD8+ T lymphocyte; cell level; cohort analysis; controlled study; coronary artery disease; cross-sectional study; diabetes mellitus; disease association; end stage renal disease; female; hemodialysis; hemodialysis patient; human; human cell; immunophenotyping; immunosenescence; inflammation; innate immunity; longitudinal study; lymphocyte differentiation; major clinical study; male; middle aged; monocyte; monocyte count; observational study; prediction; prevalence; priority journal; T lymphocyte
Publisher
BMC
Type
journal article