Seroprevalence study of Helicobacter pylori infection in patients with gastroduodenal diseases.
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
93
Journal Issue
2
Pages
122-127
Date Issued
1994
Author(s)
Abstract
To investigate Helicobacter pylori (H. pylori) infection in subjects with and without gastroduodenal diseases in Taiwan, IgG antibodies to H. pylori were examined in 136 healthy volunteers, 101 patients with non-ulcer dyspepsia, 122 gastric ulcers, 119 duodenal ulcers, and 161 gastric adenocarcinomas. The seropositivity was highest in duodenal ulcers (87.4%) (p < 0.001, as compared to healthy volunteers), followed by gastric ulcers (76.2%) (p < 0.01, as compared to healthy volunteers), but similar among gastric adenocarcinomas (60.3%), healthy volunteers (58.8%), and patients with non-ulcer dyspepsia (55.5%). Higher acquisition of H. pylori in younger patients with duodenal and gastric ulcers suggests a strong association with H. pylori. No ulcer characteristics, including number, location, and activity, were significantly statistically associated with the seropositivity of H. pylori in gastric and duodenal ulcers. Similarly, the location, extent of invasion, and histology of gastric adenocarcinoma was not significantly statistically associated with the seropositivity of H. pylori.
SDGs
Other Subjects
bacterium antibody; adenocarcinoma; adult; aged; article; duodenum disease; duodenum ulcer; dyspepsia; epidemiology; female; Helicobacter infection; Helicobacter pylori; human; immunology; male; middle aged; prevalence; stomach disease; stomach tumor; stomach ulcer; Taiwan; Adenocarcinoma; Adult; Aged; Antibodies, Bacterial; Duodenal Diseases; Duodenal Ulcer; Dyspepsia; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Prevalence; Seroepidemiologic Studies; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Taiwan
Type
journal article