|Title:||TiNiCuAg shape memory alloy films for biomedical applications||Authors:||Jhou W.-T.
|Keywords:||Calorimetry;Phase transitions;Shape memory;Thin films;X-ray diffraction||Issue Date:||2018||Journal Volume:||738||Start page/Pages:||336-344||Source:||Journal of Alloys and Compounds||Abstract:||
TiNi-based shape memory alloys (SMAs) have been largely utilized in stents, orthopedic endo-prostheses and orthodontic implants. While bacterial infection in medical implants is the most common complication, development of antibacterial TiNi-based SMAs is essential. In the present study, a novel antibacterial TiNiCuAg shape memory alloy film (SMAF) was successfully developed by adding silver into TiNiCu matrix. The structural and biological properties of TiNiCuAg SMAF, including crystal structures, phase transformation temperatures, shape memory effect, antibacterial ability and cell cytotoxicity, were systematically investigated. The results showed that the phase transformation temperature gradually decreased and silver started to precipitate with the increasing silver content. The single-stage B2 ? B19¡¬ transformation occurred in TiNiCu and Ti 51 Ni 43.5 Cu 4.5 Ag 1 films, while the two-stage B2 ? R ? B19¡¬ transformation occurred in Ti 49.6 Ni 42 Cu 6.9 Ag 1.5 , Ti 47.4 Ni 41.2 Cu 6.4 Ag 5.6 and Ti 47.7 Ni 41.2 Cu 4.1 Ag 7 films. Moreover, compared to TiNiCu films, TiNiCuAg films performed the better shape memory effect with the increasing silver content. For antibacterial tests, the TiNiCuAg films with the Ag content of 5.6 at.% had the best antibacterial ability against S. aureus and E. coli compared to those of TiNi and TiNiCu films. For cytotoxicity assay, all films maintained good biocompatibility and revealed no cell toxicity for L929 cells. As a result, excellent antibacterial ability and good biocompatibility suggested that TiNiCuAg SMAFs had potential applications for medical implant to avoid bacterial infection. ? 2017 Elsevier B.V.
|Appears in Collections:||材料科學與工程學系|
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