https://scholars.lib.ntu.edu.tw/handle/123456789/426463
標題: | Self-assembly mechanisms of nanofibers from peptide amphiphiles in solution and on substrate surfaces | 作者: | HSIEN-SHUN LIAO JING-JER LIN Liu, Yang Huang, Peng Jin, Albert Chen, Xiaoyuan |
公開日期: | 4-八月-2016 | 出版社: | ROYAL SOC CHEMISTRY | 卷: | 8 | 期: | 31 | 起(迄)頁: | 14814 | 來源出版物: | Nanoscale | 摘要: | We report the investigation of the self-assembly mechanism of nanofibers, using a small peptide amphiphile (NapFFKYp) as a model. Combining experimental and simulation methods, we identify the self-assembly pathways in the solution and on the substrates, respectively. In the solution, peptide amphiphiles undergo the nucleation process to grow into nanofibers. The nanofibers can further twist into high-ordered nanofibers with aging. On the substrates, peptide amphiphiles form nanofibers and nanosheet structures simultaneously. This surface-induced nanosheet consists of rod-like structures, and its thickness is substrate-dependent. Most intriguingly, water can transform the nanosheet into the nanofiber. Molecular dynamic simulation suggests that hydrophobic and ion-ion interactions are dominant forces during the self-assembly process. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/426463 | ISSN: | 2040-3364 | DOI: | https://api.elsevier.com/content/abstract/scopus_id/84981489633 10.1039/c6nr04672j |
顯示於: | 機械工程學系 |
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