https://scholars.lib.ntu.edu.tw/handle/123456789/426846
標題: | Effect of cold ischemia time on the early outcome of human hepatic allografts preserved with UW solution | 作者: | Furukawa, H Todo, S Imventarza, O Casavilla, A YAO-MING WU Scotti-Foglieni, C Broznick, B Bryant, J Day, R Starzl, T E |
公開日期: | 五月-1991 | 卷: | 51 | 期: | 5 | 來源出版物: | Transplantation | 摘要: | Five hundred ninety-three cadaveric livers were used for primary liver transplantation between October 24, 1987, and May 19, 1989. The grafts were procured with a combined method, using in situ cooling with cold electrolyte solution and backtable flushing with UW solution. The mean cold-ischemia time was 12.8 (range 2.4-34.7) hr. The cases were divided into 5 groups according to the cold-ischemia time: group 1: less than 10 hr (n = 223); group 2: 10-14 hr (n = 188); group 3: 15-19 hr (n = 101); group 4: 20-24 hr (n = 52); and group 5: greater than or equal to 25 hr (n = 29). There was no difference between the 5 groups in 1-year patient survival, highest SGOT in first week after operation, and SGOT and total bilirubin during the first month after operation. However, with a logistic regression model, the retransplantation rate (P = 0.001) and primary nonfunction rate (P = 0.006) significantly rose as cold-ischemia time increased, meaning that the equivalency of patient survival was increasingly dependent on aggressive retransplantation. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/426846 | ISSN: | 0041-1337 | DOI: | 10.1097/00007890-199105000-00013 |
顯示於: | 醫學系 |
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