https://scholars.lib.ntu.edu.tw/handle/123456789/427617
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chih-Ken Chu | en_US |
dc.contributor.author | Yi-Chou Tu | en_US |
dc.contributor.author | Jen-Hung Hsiao | en_US |
dc.contributor.author | Jian-He Yu | en_US |
dc.contributor.author | Chih-Kang Yu | en_US |
dc.contributor.author | Shih-Yang Chen | en_US |
dc.contributor.author | Po-Hao Tseng | en_US |
dc.contributor.author | Shuai Chen | en_US |
dc.contributor.author | Yean-Woei Kiang | en_US |
dc.contributor.author | C. C. Yang | en_US |
dc.contributor.author | CHIH-CHUNG YANG | en_US |
dc.creator | YEAN-WOEI KIANG;C. C. Yang;Yean-Woei Kiang;Shuai Chen;Po-Hao Tseng;Shih-Yang Chen;Chih-Kang Yu;Jian-He Yu;Jen-Hung Hsiao;Yi-Chou Tu;Chih-Ken Chu | - |
dc.date.accessioned | 2019-10-24T07:46:52Z | - |
dc.date.available | 2019-10-24T07:46:52Z | - |
dc.date.issued | 2016 | - |
dc.identifier.issn | 9574484 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/427617 | - |
dc.description.abstract | We demonstrate effective inactivation of oral cancer cells SAS through a combination of photothermal therapy (PTT) and photodynamic therapy (PDT) effects based on localized surface plasmon resonance (LSPR) around 1064 nm in wavelength of a Au nanoring (NRI) under femtosecond (fs) laser illumination. The PTT effect is caused by the LSPR-enhanced absorption of the Au NRI. The PDT effect is generated by linking the Au NRI with the photosensitizer of sulfonated aluminum phthalocyanines (AlPcS) for producing singlet oxygen through the LSPR-enhanced two-photon absorption (TPA) excitation of AlPcS. The laser threshold intensity for cancer cell inactivation with the applied Au NRI linked with AlPcS is significantly lower when compared to that with the Au NRI not linked with AlPcS. The comparison of inactivation threshold intensity between the cases of fs and continuous laser illuminations at the same wavelength and with the same average power confirms the crucial factor of TPA under fs laser illumination for producing the PDT effect. ? 2016 IOP Publishing Ltd. | - |
dc.relation.ispartof | Nanotechnology | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | Cells; Cytology; Diseases; Gold; Luminescence of organic solids; Nanorings; Nanostructured materials; Photodynamic therapy; Photons; Photosensitizers; Plasmons; Resonance; Two photon processes; Aluminum phthalocyanine; Cancer cells; Femtosecond (fs) laser; Localized surface plasmon resonance; Photodynamic inactivation; Photodynamic therapy (PDT); Photothermal therapy; Two photon absorption; Surface plasmon resonance; gold; indole derivative; metal nanoparticle; organometallic compound; photosensitizing agent; tetrasulfophthalocyanine aluminum; cell survival; chemistry; drug effects; human; Mouth Neoplasms; nanotechnology; photochemotherapy; surface plasmon resonance; thermotherapy; tumor cell line; Cell Line, Tumor; Cell Survival; Gold; Humans; Hyperthermia, Induced; Indoles; Metal Nanoparticles; Mouth Neoplasms; Nanotechnology; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Surface Plasmon Resonance | - |
dc.title | Combination of Photothermal and Photodynamic Inactivation of Cancer Cell through Surface Plasmon Resonance of Gold Nanoring | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1088/0957-4484/27/11/115102 | - |
dc.identifier.scopus | 2-s2.0-84959020626 | - |
dc.relation.pages | 085018 | - |
dc.relation.journalvolume | 27 | - |
dc.relation.journalissue | 11 | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Photonics and Optoelectronics | - |
crisitem.author.dept | Electrical Engineering | - |
crisitem.author.orcid | 0000-0002-3476-3802 | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
crisitem.author.parentorg | College of Electrical Engineering and Computer Science | - |
Appears in Collections: | 電機工程學系 |
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