https://scholars.lib.ntu.edu.tw/handle/123456789/431016
標題: | Quantification of the pulse wave velocity of the descending aorta using axial velocity profiles from phase-contrast magnetic resonance imaging | 作者: | HSI-YU YU Peng, Hsu-Hsia JAW-LIN WANG CHENG-YEN WEN WEN-YIH TSENG |
關鍵字: | pulse wave velocity; compliance; aorta; magnetic resonance imaging; phase contrast; axial flow velocity profile | 公開日期: | 十月-2006 | 出版社: | WILEY | 卷: | 56 | 期: | 4 | 起(迄)頁: | 876 | 來源出版物: | Magnetic resonance in medicine | 摘要: | The pulse wave velocity (PWV) of aortic blood flow is considered a surrogate for aortic compliance. A new method using phase-contrast (PC)-MRI is presented whereby the spatial and temporal profiles of axial velocity along the descending aorta can be analyzed. Seventeen young healthy volunteers (the YH group), six older healthy volunteers (the OH group), and six patients with coronary artery disease (the CAD group) were studied. PC-MRI covering the whole descending aorta was acquired, with velocity gradients encoding the in-plane velocity. From the corrected axial flow velocity profiles, PWV was determined from the slope of an intersecting line between the presystolic and early systolic phases. Furthermore, the aortic elastic modulus (Ep) was derived from the ratio of the brachial pulse pressure to the strain of the aortic diameter. The PWV increased from YH to OH to CAD (541 +/- 94, 808 +/- 184, 1121 +/- 218 cm/s, respectively; P = 0.015 between YH and OH; P = 0.023 between OH and CAD). There was a high correlation between PWV and Ep (r = 0.861, P < 0.001). Multivariate analysis showed that age and CAD were independent risk factors for an increase in the PWV. Compared to existing methods, our method requires fewer assumptions and provides a more intuitive and objective way to estimate the PWV. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/431016 | ISSN: | 0740-3194 | DOI: | 10.1002/mrm.21034 | SDG/關鍵字: | Acoustic wave velocity; Axial flow; Computer aided diagnosis; Diseases; Flow velocity; Magnetic resonance imaging; Multivariant analysis; Risk assessment; Wave propagation; Aorta; Compliance; Coronary artery disease; Multi variate analysis; Phase contrast magnetic resonance imaging; Phase contrasts; Pulse wave velocity; Velocity gradients; Blood vessels; adult; aorta flow; artery diameter; article; brachial artery; clinical article; controlled study; coronary artery disease; correlation analysis; descending aorta; female; human; male; multivariate analysis; nuclear magnetic resonance imaging; pulse pressure; pulse wave; risk factor; systole; volunteer; Young modulus |
顯示於: | 醫學系 |
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