Heart Retransplantation for Heart Allograft Failure in Chinese Heart Transplant Recipients: NTUH Experience
Journal
Transplantation Proceedings
Journal Volume
38
Journal Issue
7
Pages
2147-2148
Date Issued
2006
Author(s)
Ko W.J.
Lin F.Y.
Chu S.H.
Abstract
We investigated the short- and long-term results after heart retransplantation in terms of different causes of heart allograft failure. We sought to establish the data of heart retransplantation in Chinese compared with Western counterparts due to differences in heart allograft vasculopathy. From March 1995 to May 2005, eight heart transplantation recipients with allograft failure underwent retransplantation. Heart allograft failure was due to coronary vasculopathy (CAV) in six patients (75%) and acute rejection in two patients (25%). The mean interval to retransplantation was 32 to 84 months (mean 54.3 months). There were five patients who survived after heart retransplantation for CAV and no patient survived after an earlier diagnosis of acute rejection. Heart retransplantation is a feasible method with acceptable long-term survival rate for heart allograft failure. After careful pretransplant evaluation, retransplantation is acceptable. The survival after retransplantation for CAV is notably great than that after acute rejection. Heart retransplantation is the only way for patients who have cardiac allograft failure to achieve long-term survival. ? 2006 Elsevier Inc. All rights reserved.
SDGs
Other Subjects
acute graft rejection; angiocardiography; article; cardiac allograft vasculopathy; Chinese; clinical article; coronary artery disease; early diagnosis; graft failure; graft recipient; heart muscle biopsy; heart transplantation; human; male; priority journal; retransplantation; survival rate; survival time; Adult; Biopsy; China; Graft Rejection; Heart Transplantation; Humans; Male; Middle Aged; Reoperation; Retrospective Studies; Survival Analysis; Taiwan; Transplantation, Homologous; Treatment Failure
Type
journal article