Periodic lateralized epileptiform discharges of pediatric patients in Taiwan
Journal
Pediatric Neurology
Journal Volume
28
Journal Issue
2
Pages
100-103
Date Issued
2003
Author(s)
Abstract
Periodic lateralized epileptiform discharges are special electroencephalographic abnormalities present in adults with stroke, brain tumor, intracranial hemorrhage, or other rare etiologies. Few reports focused on the etiologies in pediatric patients. We retrospectively reviewed 8002 of our pediatric electroencephalographic records for the past 12 years and listed all associated illness and their outcomes. Forty-four children with periodic lateralized epileptiform discharges were collected. We found that there was an obvious difference in etiologies of our pediatric patients from those reported in the literature. Nearly two thirds of our patients (28 children) were associated with central nervous system infections. The other etiologies included head injury, encephalopathy, epilepsy, and others. Herpes simplex virus was responsible for two thirds (12) of the 18 children with identified pathogens causing a central nervous system infection. Ten patients failed to have a defined pathogen. Periodic lateralized epileptiform discharges have a different clinical significance in pediatric patients than in adults. In Taiwan, central nervous system infection is the most common etiology of periodic lateralized epileptiform discharges in pediatric patients. Herpes simplex virus, although the most common pathogen, should not be considered to be the only cause of encephalitis in children with periodic lateralized epileptiform discharges. ? 2003 by Elsevier Inc. All rights reserved.
SDGs
Other Subjects
adolescent; arteriovenous malformation; article; brain disease; brain infarction; central nervous system infection; child; clinical article; Cytomegalovirus; electroencephalography; epidemic encephalitis; epilepsy; epileptic discharge; female; head injury; herpes simplex encephalitis; Herpes simplex virus; human; infant; leukodystrophy; male; meningoencephalitis; metabolic disorder; pediatrics; priority journal; Taiwan
Publisher
Elsevier Inc.
Type
journal article