Epidemiology and comorbidities of patients with chronic urticaria in Taiwan: A nationwide population-based study
Journal
Journal of Dermatological Science
Journal Volume
88
Journal Issue
2
Pages
192-198
Date Issued
2017
Author(s)
Abstract
Background Comprehensive data regarding the epidemiology of chronic urticaria (CU) in general populations are scant. Objectives To investigate the prevalence, incidence, and comorbidities of CU in general population. Methods The data were sourced from the National Health Insurance Research Database (NHIRD) for 2009–2012. Patients who had a primary/secondary ICD-9-CM diagnosis code of 708.1, 708.8, or 708.9 during the year with at least two outpatient visits and an antihistamine prescription, were identified as the cases of CU for each year. The incidence, persistence and comorbidities of CU were examined. Results The prevalence of CU ranged from 0.69% to 0.79% for each year from 2009 to 2012, and the incidence was around 0.50% per year from 2010 to 2012. Comparing to the Standard Population, the standardized prevalence ratios (SPRs) for the rheumatic diseases, thyroid disorders, inflammatory diseases, and psychiatric disorders among CU patients were 2.74, 1.81, 1.57 and 1.87, respectively. Conclusion The prevalence of CU in Taiwan is about 0.69-0.79%. CU is associated with a significantly increased risk of psychiatric disorders, inflammatory diseases, thyroid disorders, and rheumatic diseases. Except for thyroid disorders, the prevalence of these comorbidities tends to increase the longer CU persists. ? 2017
Subjects
Comorbidity
Psychiatric disorders
Rheumatic diseases
Thyroid disorders
Urticaria
SDGs
Other Subjects
antihistaminic agent; adult; age distribution; Article; chronic urticaria; comorbidity; female; human; inflammatory disease; major clinical study; male; mental disease; outpatient; population research; prescription; prevalence; priority journal; rheumatic disease; risk assessment; risk factor; sex ratio; Taiwan; thyroid disease; aged; chronic disease; comorbidity; incidence; inflammation; mental disease; middle aged; prevalence; rheumatic disease; thyroid disease; time factor; urticaria; young adult; Adult; Aged; Chronic Disease; Comorbidity; Female; Humans; Incidence; Inflammation; Male; Mental Disorders; Middle Aged; Prevalence; Rheumatic Diseases; Taiwan; Thyroid Diseases; Time Factors; Urticaria; Young Adult
Publisher
Elsevier Ireland Ltd
Type
journal article