Ofuji's disease: A review of 34 patients in 10 years
Journal
Dermatologica Sinica
Journal Volume
26
Journal Issue
2
Pages
65-74
Date Issued
2008
Author(s)
Wu J.-J.
Abstract
Ofuji's disease is clinically characterized by chronic and recurrent annular clusters of sterile follicular papules and pustules superimposed on plaques with central clearing and peripheral extension. Indomethacin is considered to be a first choice of treatment, but the pathogenesis of this disease is still obscure. Although most cases of Ofuji's disease have been reported in Japanese people, it is not rare in Taiwan according to our clinical experience. In this study, we reviewed 34 patients with biopsy-proven Ofuji's disease who came to our clinic over the past decade. Extrafacial involvement was noted in 15 of 34 patients (44%), and 7 had palmoplantar lesions. We emphasize on the features of extra-facial involvement, especially the palmoplantar lesions, because it may lead to clinical and pathological confusion in diagnosing the disease. We also found indomethacin seemed to have a higher effective rate (89%) as compared to other treatments in our cases.
Subjects
Eosinophilic folliculitis; Extra-facial involvement; Ofuji's disease
SDGs
Other Subjects
antihistaminic agent; betamethasone dipropionate; betamethasone valerate; clobetasol propionate; colchicine; dapsone; doxycycline; fluticasone propionate; fusidic acid; indometacin; itraconazole; minocycline; naproxen; prednisolone; tacrolimus; tetracycline; adolescent; adult; arm; clinical article; clinical feature; controlled study; drug dose reduction; drug efficacy; drug substitution; drug withdrawal; erythema; female; folliculitis; foot sole; hand palm; histopathology; human; human tissue; leg; male; medical record; monotherapy; nail dystrophy; ofuji disease; papule; pompholyx; pruritus; pustule; pustulosis palmoplantaris; retrospective study; review; skin biopsy; treatment outcome; treatment response; trunk
Type
review