Vitiligo Universalis Associated with Evans Syndrome and Antiphospholipid Syndrome: A Case Report and Review of the Literature
全身性白斑合併Evans徵候群及antiphospholipid徵候群：病例報告與文獻回顧
Journal
Dermatologica Sinica
Journal Volume
22
Journal Issue
1
Pages
93-99
Date Issued
2004
Author(s)
Abstract
The pathogenesis of vitiligo has been proposed as a destruction of melanocytes by autoimmune processes. Evans syndrome is the combination of autoimmune hemolytic anemia and immune-mediated thrombocytopenia. The antiphospholipid syndrome is characterized by arterial/venous thrombosis, recurrent pregnancy loss, or thrombocytopenia in the presence of antiphospholipid antibodies. We present a case of vitiligo universalis associated with Evans syndrome and antiphospholipid syndrome, the association of which has not been reported before. The association of multiple autoimmune diseases in our case also support the theory that vitiligo may result from immune dysregulation.
SDGs
Type
journal article