Extracellular matrix-derived peptides and myocardial repair
Journal
Cell Adhesion and Migration
Journal Volume
5
Journal Issue
2
Pages
111-113
Date Issued
2011
Author(s)
Abstract
Repairing cardiac tissue remains one of the most challenging goals in tissue engineering. Here, we discuss ways whereby we sought to treat myocardial infarctions using extracellular-matrix derived peptides. Using an ischemia/reperfusion myocardial infarction rodent model, we targeted these extracellular matrix-derived peptides to the myocardial infarct site and were able to induce angiogenesis and alter the negative remodeling seen after an acute myocardial infarction. Our results indicate a potentially new strategy for repairing damaged tissue.
SDGs
Type
other