Two distinct Pseudomonas effector proteins interact with the Pto kinase and activate plant immunity
Journal
Cell
Journal Volume
109
Journal Volume
109
Journal Issue
5
Journal Issue
5
Pages
589-598
Start Page
589
End Page
598
ISSN
00928674
Date Issued
2002-05-31
Author(s)
Abstract
The Pto serine/threonine kinase of tomato confers resistance to speck disease by recognizing strains of Pseudomonas syringae that express the protein AvrPto. Pto and AvrPto physically interact, and this interaction is required for activation of host resistance. We identified a second Pseudomonas protein, AvrPtoB, that interacts specifically with Pto and is widely distributed among plant pathogens. AvrPtoB is delivered into the plant cell by the bacterial type III secretion system, and it elicits Pto-specific defenses. AvrPtoB has little overall sequence similarity with AvrPto. However, AvrPto amino acids, which are required for interaction with Pto, are present in AvrPtoB and required for its interaction with Pto. Thus, two distinct bacterial effectors activate plant immunity by interacting with the same host protein kinase through a similar structural mechanism.
Publisher
Elsevier B.V.
Type
journal article