https://scholars.lib.ntu.edu.tw/handle/123456789/448853
標題: | Modeling the impact of control measures on tuberculosis infection in senior care facilities | 作者: | CHUNG-MIN LIAO Lin Y.-J. Cheng Y.-H. |
關鍵字: | Control measures; Indoor air quality; Modeling; Senior care facilities; Transmission; Tuberculosis | 公開日期: | 2013 | 卷: | 59 | 起(迄)頁: | 66-75 | 來源出版物: | Building and Environment | 摘要: | Tuberculosis (TB) is among the top ten causes of death worldwide. The impacts of potential control measures on TB infection in senior care facilities are poorly understood in Taiwan region. The purpose of this paper was to assess the impacts of potential control strategies for reducing the risk for TB infection among elderly in senior care facilities and to provide the suggestions for sound TB infection control measures that should be implemented in all senior care facilities with aged people suspected of having infectious TB. We proposed an integrated-level mathematical model, incorporating the TB transmission dynamics, the Wells-Riley mathematical equation, and the competing-risks model to quantify the potential spread of TB bacilli in senior care facilities. We found that individuals living in hospital-based nursing homes had much higher exposure to TB than those in long-term and domiciliary care facilities. We showed that the proposed combinations of engineering control measures (e.g., ventilation and ultraviolet germicidal irradiation) with personal protection (e.g., surgical mask) guarantee the provision of a reliable control strategy to decrease the transmission potential and spread rate of TB bacilli aerosols in senior care facilities in that the efficacies range from 45 to 90%. The introduction of appropriate TB transmission control measures may decrease TB annual incidence in senior care facilities by as much as 76-90% of tuberculin skin test (TST) conversion. Our study implicated that sound TB infection control measures, including diagnosis and prompt treatment of infectious cases should be prioritized. ? 2012 Elsevier Ltd. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/448853 | ISSN: | 0360-1323 | DOI: | 10.1016/j.buildenv.2012.08.008 | SDG/關鍵字: | Causes of death; Control measures; Engineering controls; Indoor air quality; Infection control; Mathematical equations; Nursing homes; Personal protection; Potential control; Reliable control; Transmission control; Transmission dynamics; Transmission potential; Tuberculosis; Tuberculosis infection; Ultraviolet germicidal irradiations; Bacilli; Hospitals; Indoor air pollution; Mathematical models; Models; Transmissions; Tubes (components); aerosol; air quality; disease control; disease transmission; indoor air; numerical model; tuberculosis; disease incidence; disease spread; elderly population; flow field; flow modeling; health risk; Taiwan; Bacilli (class) |
顯示於: | 生物環境系統工程學系 |
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