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  4. Multiphysics modeling of liver tumor ablation by high intensity focused ultrasound
 
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Multiphysics modeling of liver tumor ablation by high intensity focused ultrasound

Journal
Communications in Computational Physics
Journal Volume
18
Journal Issue
4
Pages
1050-1071
Date Issued
2015
Author(s)
Solovchuk, M.
Sheu, T.W.-H.
Thiriet, M.
TONY W. H. SHEU  
DOI
10.4208/cicp.171214.200715s
URI
https://scholars.lib.ntu.edu.tw/handle/123456789/451684
URL
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84944383704&doi=10.4208%2fcicp.171214.200715s&partnerID=40&md5=b04966c3a9ba5402d5a0d51db2b481ba
Abstract
High intensity focused ultrasound is a rapidly developing technology for the ablation of tumors. Liver cancer is one of the most common malignancies worldwide. Since liver has a large number of blood vessels, blood flow cooling can reduce the necrosed volume and may cause regeneration of the tumor to occur. All cancer cells should be ablated without damaging of the critical tissues. Today, treatment planning tools consider liver as a homogeneous organ. This paper is a step towards the development of surgical planning platform for a non-invasive HIFU tumor ablative therapy in a real liver geometry based on CT/MRI image. This task requires coupling of different physical fields: acoustic, thermal and hydrodynamic. These physical fields can influence each other. In this paper we illustrate how a computational model can be used to improve the treatment efficiency. In large blood vessel both convective cooling and acoustic streaming can change the temperature considerably near blood vessel. The whole tumor ablation took only 30 seconds in the considered simulation case, which is very small comparing with the current treatment time of several hours. Through this study we are convinced that high ultrasound power and nonlinear propagation effects with appropriate treatment planning can sufficiently reduce the treatment time. ? 2015 Global-Science Press.
Subjects
blood flow; computational surgery; focused ultrasound; liver tumor; Multiphysics and multiscale model
SDGs

[SDGs]SDG3

Type
conference paper

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