The molecular genetic background leading to the formation of the human erythroid-specific Xga/CD99 blood groups
Journal
Blood Advances
Journal Volume
2
Journal Issue
15
Pages
1854 - 1864
Date Issued
2018
Author(s)
Yeh, Chih-Chun
Chang, Ching-Jin
Twu, Yuh-Ching
Chu, Chen-Chung
Liu, Bi-Shan
Huang, Ji-Ting
Hung, Shu-Ting
Chan, Yung-Syu
Tsai, Yi-Jui
Lin, Sheng-Wei
Lin, Marie
Abstract
Key Points SNP rs311103 is associated with human erythroid-specific Xga/CD99 blood group phenotypes. The erythroid GATA1 factor binds to the polymorphic rs311103 genomic region differentially, which affects transcriptional activity.
SDGs
Type
journal article