The prevalence and risk factors of nocturia in China, South Korea, and Taiwan: Results from a cross-sectional, population-based study
Journal
World Journal of Urology
Journal Volume
36
Journal Issue
11
Pages
1853-1862
Date Issued
2018
Author(s)
Chuang Y.-C.
Lee K.-S.
Yoo T.K.
Liao L.
Wang J.-Y.
Liu M.
Sumarsono B.
Jong J.J.
Abstract
Purpose To examine the prevalence, symptomatology, and risk factors for nocturia using data from an internet-based questionnaire conducted in China, South Korea, and Taiwan. Methods Data from a cross-sectional, population-representative, internet-based study conducted among men and women aged ? 40 years were analysed post hoc. Nocturia prevalence and bother were analysed by sex and age group, and with regard to comorbid conditions and lower urinary tract symptoms (LUTS). Multivariate and univariate logistic regression models to identify risk factors for nocturia were constructed, with nocturia involving ? 2 nocturnal voids as the dependent variable. Results Among the 8284 participants, the prevalence of nocturia involving ? 1, ? 2, or ? 3 voids was slightly higher for women (76.1, 37.3, and 17.5%, respectively) compared with men (74.0, 34.5, and 15.5%, respectively). The prevalence and associated bother of nocturia increased with age. Greater proportions of patients with comorbid conditions or wet/ more severe overactive bladder syndrome (OAB) experienced nocturia than those without. Multivariate analysis identified that female sex, age > 60 years, diabetes, cardiac disease, body mass index, International Prostate Symptom Score (IPSS) voiding score, stress urinary incontinence, wet OAB, and Hospital Anxiety And Depression Scale (HADS) anxiety score were associated with ? 2 nocturnal voids. Hypertension was associated with ? 2 nocturnal voids in women but not men, and alcohol consumption in men but not women. Conclusions Nocturia is a common and bothersome condition affecting a large proportion of men and women aged ? 40 years in China, South Korea, and Taiwan. Factors associated with nocturia included age, sex, comorbid conditions, and LUTS. Trial registration This study is registered at ClinicalTrials.gov: NCT02618421. ? Springer-Verlag GmbH Germany, part of Springer Nature 2018.
SDGs
Other Subjects
adult; age distribution; aged; China; cross-sectional study; female; human; lower urinary tract symptom; male; middle aged; multivariate analysis; nocturia; overactive bladder; prevalence; quality of life; questionnaire; risk assessment; severity of illness index; sex ratio; South Korea; statistical model; stress incontinence; Taiwan; Adult; Age Distribution; Aged; China; Cross-Sectional Studies; Female; Humans; Logistic Models; Lower Urinary Tract Symptoms; Male; Middle Aged; Multivariate Analysis; Nocturia; Prevalence; Quality of Life; Republic of Korea; Risk Assessment; Severity of Illness Index; Sex Distribution; Surveys and Questionnaires; Taiwan; Urinary Bladder, Overactive; Urinary Incontinence, Stress
Type
journal article