The association between polypronucleate zygote formation with certain motion characteristics of sperm and IVF outcome
Journal
Journal of Assisted Reproduction and Genetics
Journal Volume
25
Journal Issue
1
Pages
35-41
Date Issued
2008
Author(s)
Abstract
Purpose: To determine the efficiency of sperm motion characteristics as predictors for normal (2PN) and polypronulceate (PPN) zygotes in IVF. Methods: A retrospective cohort analysis for a total of 230 couples undergoing IVF treatment in a single infertility center. Result(s): Subsequent to semen analysis and hemizona assay, unexpected fertilization failure would appear to have occurred only extremely rarely (1/236, 0.4%). The rate of PPN, however, did arise and appeared to be related to certain sperm motion characteristics, such as lateral head displacement and concentration of progressive motile sperm. Interestingly, the patients featuring a high PPN rate (>20%) was associated with a greater pregnancy rate than those featuring a low PPN rate (<20%). Conclusion: The sperm motion characteristics examined herein could be utilized to predict the rate of PPN in IVF. In order to enhance the rate of 2PN and maintain the relative high rate of clinical pregnancy, an efficient method needs further investigation and development. © 2007 Springer Science+Business Media, LLC.
SDGs
Type
journal article