https://scholars.lib.ntu.edu.tw/handle/123456789/454550
標題: | Pregnancy achieved by intracytoplasmic sperm injection using cryopreserved vasal-epididymal sperm from a man with spinal cord injury | 作者: | SHEE-UAN CHEN JENG-YI SHIEH MEN-LUH YEN HONG-CHIANG CHANG HONG-NERNG HO YU-SHIH YANG |
公開日期: | 1998 | 卷: | 79 | 期: | 2 | 起(迄)頁: | 218-221 | 來源出版物: | Archives of Physical Medicine and Rehabilitation | 摘要: | Anejaculation and poor semen quality are two major causes of infertility in men with spinal cord injury (SCI). The poor motility of retrieved sperm usually has low fertilization potential and is thought to be unfavorable for cryopreservation. This report describes a pregnancy after intracytoplasmic sperm injection (ICSI) with cryopreserved vasal-epididymal sperm from a man with SCI and anejaculation. An attempt was made to obtain sperm through electroejaculation, but no motile sperm were found in two trials. Therefore, the subject underwent vasal aspiration. The retrieved sperm had a concentration of 26 x 106/mL and a motility of 3%. ICSI was considered to be the best choice for the couple, but the wife did not become pregnant in the first cycle of treatment. A successful pregnancy was achieved by ICSI in the second cycle using frozen-thawed sperm, supernumerary in the previous cycle, with a density of 5 x 106/mL and 1% motility. A set of healthy twins, one boy and one girl, were delivered via cesarean section at 36 weeks of gestation. Complementary to other assisted reproductive techniques, ICSI may provide men with SCI a greater opportunity to father children. The supernumerary sperm, regardless of quality, should be cryopreserved to avoid the necessity and risk of repeated assisted ejaculations and aspirations of the genital tract. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/454550 | ISSN: | 0003-9993 | DOI: | 10.1016/S0003-9993(98)90303-3 | SDG/關鍵字: | buserelin acetate; chorionic gonadotropin; gonadorelin agonist; human menopausal gonadotropin; unclassified drug; urofollitropin; adult; article; case report; human; infertility therapy; intracytoplasmic sperm injection; male; male infertility; paraplegia; pregnancy; reproduction; spinal cord injury; treatment outcome; twin pregnancy |
顯示於: | 醫學系 |
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