Incorporation of carbon dioxide into phthalides via ligand-free copper-catalyzed direct carboxylation of benzoxasiloles
Journal
Green Chemistry
Journal Volume
19
Journal Issue
11
Pages
2501
Date Issued
2017
Author(s)
Abstract
The direct carboxylation of benzoxasiloles with carbon dioxide proceeded smoothly under mild conditions using copper iodide as a catalyst to afford phthalides after an acid work-up. Broad substrate scope and application of this methodology for the synthesis of natural products highlight the synthetic utility of this protocol.
SDGs
Publisher
ROYAL SOC CHEMISTRY
Type
journal article