Pregnancy achieved by intracytoplasmic sperm injection using cryopreserved semen from a man with testicular cancer
Journal
Human Reproduction
Journal Volume
11
Journal Issue
12
Pages
2645-2647
Date Issued
1996
Author(s)
Abstract
A successful pregnancy was achieved by intracytoplasmic sperm injection (ICSI) using cryopreserved semen from a man with testicular cancer. He was a victim of right testicular seminoma, and was azoospermic after right orchidectomy and radiotherapy. The wife had had three successive failures of intrauterine insemination (IUI) using semen that was cryopreserved before radiotherapy. The couple then underwent in-vitro fertilization (IVF) treatment. ICSI was performed because the sperm motility was extremely poor after thawing. Eight of 12 injected oocytes had normal fertilization and embryo cleavage. After replacement of four embryos, a singleton pregnancy developed. She delivered a healthy male baby at 39 weeks gestation. In addition to IUI and IVF, ICSI further provides male patients with cancer an improved chance of fathering a child. Any men diagnosed with cancer who have not yet finished their families should have their spermatozoa frozen before treatment, regardless of its quality.
SDGs
Other Subjects
adult; article; azoospermia; case report; cryopreservation; female; fertilization in vitro; human; intracytoplasmic sperm injection; intrauterine insemination; male; newborn; oocyte cleavage; orchiectomy; pregnancy; seminoma; sperm; spermatozoon motility; testis cancer
Type
journal article