Repository logo
  • English
  • 中文
Log In
Have you forgotten your password?
  1. Home
  2. College of Medicine / 醫學院
  3. School of Medicine / 醫學系
  4. Does the loop electrosurgical excision procedure adversely affect the histopathological interpretation of cervical conization specimens?
 
  • Details

Does the loop electrosurgical excision procedure adversely affect the histopathological interpretation of cervical conization specimens?

Journal
Acta Obstetricia et Gynecologica Scandinavica
Journal Volume
73
Journal Issue
9
Pages
726-729
Date Issued
1994
Author(s)
RUEY-JIEN CHEN  
Lee E.F
JIN-CHUNG SHIH  
DOI
10.3109/00016349409029412
URI
https://scholars.lib.ntu.edu.tw/handle/123456789/460839
Abstract
Objective. To assess the suitability of conized specimens obtained by loop electrosurgical excision procedure for histopathological interpretation. Methods. We evaluated the histological pictures of 215 tissue sections obtained by loop electrosurgical excision procedure. These sections came from 32 cases of patients with various degrees of cervical intraepithelial neoplasia. All women included in our study had a satisfactory colposcopy and no cytological or colposcopic evidence of invasive cancer. We quantified the thickness of thermal damage in the tissue sections using a stage?mounted. calibrated grid microscope. Results. At its greatest extent, thermal damage occurring next to incision lines ranged from 160 to 520 μ (mean 762, SE 14 μ). Two different zones of thermal damage were produced by LEEP: the carbonization and coagulation zones. The carbonization zone was located at the outermost layer and was very thin. measuring from 10 to 30 μ in depth. The coagulation zone was adjacent to the carbonization zone, was eosinophilic, and was significantly deeper than the carbonization zone at its points of greatest thickness (150 to 500 μ; p<0.0001, Student's t?test). The depth of the coagulation zone correlated significantly with the depth of the carbonization zone (p = 0.041. least linear correlation). Tissue distortion was present in 53% (17/32) of the cases, and appeared only in the coagulation zone. Conclusion. Tissue structure from the diseased portions of the conized specimens was generally veil preserved. The area of thermal damage was limited and thus did not result in diagnostic problems. We conclude that LEEP is a reliable method for obtaining tissue samples for histopathological examination. 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted
SDGs

[SDGs]SDG3

Other Subjects
adult; article; clinical article; colposcopy; electrosurgery; eosinophil; female; histopathology; human; human tissue; priority journal; surgical technique; thermal injury; thickness; tissue section; uterine cervix carcinoma in situ; uterine cervix dysplasia; Adult; Cervical Intraepithelial Neoplasia; Cervix Neoplasms; Cervix Uteri; Electrodes; Electrosurgery; Female; Human; Specimen Handling
Type
journal article

臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

  • 請確認所上傳的全文是原創的內容,若該文件包含部分內容的版權非匯入者所有,或由第三方贊助與合作完成,請確認該版權所有者及第三方同意提供此授權。
    Please represent that the submission is your original work, and that you have the right to grant the rights to upload.
  • 若欲上傳已出版的全文電子檔,可使用Open policy finder網站查詢,以確認出版單位之版權政策。
    Please use Open policy finder to find a summary of permissions that are normally given as part of each publisher's copyright transfer agreement.
  • 網站簡介 (Quickstart Guide)
  • 使用手冊 (Instruction Manual)
  • 線上預約服務 (Booking Service)
  • 方案一:臺灣大學計算機中心帳號登入
    (With C&INC Email Account)
  • 方案二:ORCID帳號登入 (With ORCID)
  • 方案一:定期更新ORCID者,以ID匯入 (Search for identifier (ORCID))
  • 方案二:自行建檔 (Default mode Submission)
  • 方案三:學科館員協助匯入 (Email worklist to subject librarians)

Built with DSpace-CRIS software - Extension maintained and optimized by 4Science