Pancreatoblastoma: Two case reports from a medical center in Taiwan
Journal
Journal of Pediatric Hematology/Oncology
Journal Volume
32
Journal Issue
3
Pages
243-245
Date Issued
2010
Author(s)
Huang Y.-L.
Lin K.-H.
Lin D.-T.
Abstract
Although pancreatoblastoma (PB) is an extremely rare tumor, it is the most common pancreatic tumor in children. We reported 2 cases of PB treated at a medical center in Taiwan. One was a 3.5-year-old boy who presented with abdominal pain. Physical examination demonstrated abdominal masses. Multiple pancreatic and hepatic masses were noted by magnetic resonance imaging. He underwent surgical resection but tumor could not be removed completely, which was confirmed by the pathology. He received chemotherapy consisting of cisplatin and doxorubicin after the surgery but the tumor progressed rapidly. He died of progressive disease and sepsis. The other case was a 4-year-old boy presented with abdominal pain. Computed tomography showed pancreatic tumor. He underwent surgical resection and pathology showed PB. He received chemotherapy after complete tumor resection. He is disease free till now. Complete tumor resection is the major difference of these 2 patients and is the most important factor affecting the outcome. Copyright ? 2010 by Lippincott Williams & Wilkins.
SDGs
Other Subjects
antineoplastic agent; cisplatin; cyclophosphamide; doxorubicin; vincristine; abdominal mass; abdominal pain; article; case report; child; computer assisted tomography; drug dose increase; drug substitution; drug withdrawal; echography; histopathology; human; human tissue; laparotomy; liver metastasis; lung nodule; lymphadenopathy; male; multiple cycle treatment; nuclear magnetic resonance imaging; pancreas resection; pancreas tumor; pancreatoblastoma; preschool child; priority journal; sepsis; Taiwan; treatment outcome; tumor growth; tumor volume; vomiting; Antineoplastic Combined Chemotherapy Protocols; Child, Preschool; Cisplatin; Doxorubicin; Fatal Outcome; Humans; Liver Neoplasms; Male; Pancreatic Neoplasms; Taiwan; Tomography, X-Ray Computed; Treatment Outcome
Type
journal article