https://scholars.lib.ntu.edu.tw/handle/123456789/466737| Title: | Clinical Correlates of Unawareness of Deficits Among Patients With Dementia Due to Alzheimer's Disease | Authors: | Chen, Yi-Lung Chen, Hui-Mei Huang, Mei-Feng Yeh, Yi-Chun Yen, Cheng-Fang Chen, Cheng-Sheng HUI-MEI CHEN |
Keywords: | Alzheimer's disease; Apathy; Depression; Unawareness of deficits | Issue Date: | 2014 | Journal Volume: | 29 | Journal Issue: | 6 | Start page/Pages: | 533-539 | Source: | American Journal of Alzheimers Disease and Other Dementias | Abstract: | Background: To investigate the associations between unawareness of deficits and clinical correlates, including apathy and depression, among patients with dementia due to Alzheimer's disease (AD). Methods: Fifty-five patients with AD were enrolled. Unawareness of memory deficits and psychosis or behavior problems was assessed. The Apathy Evaluation Scale informant version and the Cornell Scale for Depression in Dementia (CSDD) were used to measure apathy and depression, respectively. Results: In all, 32 (57.2%) and 27 (49.1%) participants were identified as being unaware of memory deficits and psychosis or behavior problems, respectively. Unawareness of memory deficits was associated with lower scores on the Mini-Mental State Examination (MMSE) and higher scores on the CSDD. Unawareness of psychosis or behavior problems was associated with lower scores on the MMSE. Conclusion: Unawareness of deficits among patients with AD was common. The 2 domains of unawareness showed different characteristics and may possibly present different etiologies. ? The Author(s) 2014. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/466737 | ISSN: | 1533-3175 | DOI: | 10.1177/1533317514523484 | SDG/Keyword: | age; aged; Alzheimer disease; amnesia; apathy; Article; behavior disorder; cognition; Cornell Scale for Depression in Dementia; dementia; depression; descriptive research; female; human; major clinical study; male; Mini Mental State Examination; psychosis; sex difference; adult; Alzheimer disease; complication; depression; Memory Disorders; middle aged; neuropsychological test; psychological rating scale; severity of illness index; very elderly; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Depression; Female; Humans; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Severity of Illness Index [SDGs]SDG3 |
| Appears in Collections: | 園藝暨景觀學系 |
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