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  3. Anatomy and Cell Biology / 解剖學暨細胞生物學研究所
  4. Normal values and symptom correlation of a simplified oatmeal-based gastric emptying study in the Chinese population
 
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Normal values and symptom correlation of a simplified oatmeal-based gastric emptying study in the Chinese population

Journal
Journal of Gastroenterology and Hepatology (Australia)
Journal Volume
29
Journal Issue
11
Pages
1873-1882
Date Issued
2014
Author(s)
PING-HUEI TSENG  
YEN-WEN WU  
YI-CHIA LEE  
MEI-FANG CHENG  
KAI-YUAN TZEN 
HSIU-PO WANG  
Lin J.-T.
SUNG-TSANG HSIEH  
WEI-SHIUNG YANG  
MING-SHIANG WU  
DOI
10.1111/jgh.12640
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84912039242&doi=10.1111%2fjgh.12640&partnerID=40&md5=60391b5191a0e098758df554f1ade508
https://scholars.lib.ntu.edu.tw/handle/123456789/467741
Abstract
Background and Aim: Instant oatmeal has been proposed as a good alternative to the standardized low-fat egg white test meal for gastric emptying studies. We aim to establish normal values of oatmeal-based gastric emptying scintigraphy and test its correlation with gastroparesis symptoms in the Chinese population. Methods: This study prospectively enrolled 60 healthy volunteers, 30 functional dyspepsia and 30 diabetes patients with gastroparesis symptoms. All participants were evaluated using the Gastroparesis Cardinal Symptom Index. Each participant ingested instant oatmeal mixed with 1 mCi of 99mTc diethylenetriaminepentacetic acid, and serial imaging was immediately acquired for 3h in the supine position using a left anterior oblique projection. Time-activity curves were generated and quantitative parameters were determined. Normal values were established from healthy volunteers and further applied in the symptomatic patients. Results: All participants finished the test meal and tolerated the procedure well. All gastric emptying parameters were not significantly affected by age or gender. Values above the 95th percentile of T1/2, gastric retention at 1, 2, and 3 h (85 min, 65%, 28%, and 8%, respectively) were indicative of delayed gastric emptying. Values below the 5th percentile of gastric retention at 0.5 and 1h (40% and 15%, respectively) were indicative of rapid gastric emptying. The lower gastric retention limit at 0.5 and 1h were 40% and 15%, respectively. Four (13.3%) diabetes and four (13.3%) functional dyspepsia patients had delayed emptying while three diabetes patients (10%) had rapid emptying. Gastric emptying parameters correlated best with vomiting (r=0.621) and nausea (r=0.566) in diabetes patients. Conclusions: We established normal values of oatmeal-based gastric emptying scintigraphy and observed good correlation with cardinal gastroparesis symptoms in the Chinese population. ? 2014 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.
SDGs

[SDGs]SDG3

Other Subjects
pentetate technetium tc 99m; radiopharmaceutical agent; adult; Asian continental ancestry group; diagnostic use; digestive system examination; female; human; male; middle aged; oat; pathophysiology; prospective study; scintiscanning; stomach emptying; stomach paresis; young adult; Adult; Asian Continental Ancestry Group; Avena sativa; Diagnostic Techniques, Digestive System; Female; Gastric Emptying; Gastroparesis; Humans; Male; Middle Aged; Prospective Studies; Radiopharmaceuticals; Technetium Tc 99m Pentetate; Young Adult
Publisher
Blackwell Publishing
Type
journal article

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