https://scholars.lib.ntu.edu.tw/handle/123456789/468705
標題: | NTU-DSI-122: A diffusion spectrum imaging template with high anatomical matching to the ICBM-152 space | 作者: | Hsu Y.-C. Lo Y.-C. Chen Y.-J. Wedeen V.J. WEN-YIH TSENG |
公開日期: | 2015 | 出版社: | John Wiley and Sons Inc. | 卷: | 36 | 期: | 9 | 起(迄)頁: | 3528-3541 | 來源出版物: | Human Brain Mapping | 摘要: | A diffusion-weighted (DW) template in a standard coordinate system is often necessary for the analysis of white matter (WM) structures using DW images. Although several DW templates have been constructed in the ICBM-152 space, a template for diffusion spectrum imaging (DSI) is still lacking. In this study, we developed a DSI template in the ICBM-152 space from 122 healthy adults. This high quality template, NTU-DSI-122, was built through incorporating the macroscopic anatomical information using high-resolution T1-weighted images and the microscopic structural information obtained from DSI datasets. Two evaluations were conducted to examine the quality of NTU-DSI-122. The first evaluation examined the anatomical consistency of NTU-DSI-122 in matching to the ICBM-152 coordinate system. The results showed that this template matched to the ICBM-152 templates very well across the whole brain, not only in the deep white matter regions as other DW templates but also in the superficial white matter regions. In the second evaluation, a large number of independent diffusion tensor imaging (DTI) datasets were registered to the DTI template derived from NTU-DSI-122. The examination was performed by quantifying the anatomical consistency among the registered DTI datasets. The results showed that using NTU-DSI-122 as the registration template the registered DTI datasets can achieve high anatomical alignment. Both evaluations demonstrate that NTU-DSI-122 is a useful high quality DW template. Therefore, NTU-DSI-122 can serve as a representative DSI dataset for a healthy adult population, and will be of potential value for brain research and clinical applications. The NTU-DSI-122 template is available at http://www.nitrc.org/projects/ntu-dsi-122/. ? 2015 Wiley Periodicals, Inc. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84939467120&doi=10.1002%2fhbm.22860&partnerID=40&md5=4b4b34eb135c9b1f11b9b5d16fca82af https://scholars.lib.ntu.edu.tw/handle/123456789/468705 |
ISSN: | 1065-9471 | DOI: | 10.1002/hbm.22860 | SDG/關鍵字: | adult; Article; brain region; comparative study; diffusion spectrum imaging; diffusion tensor imaging; female; human; human experiment; image processing; image quality; male; neuroanatomy; neuroimaging; normal human; nuclear magnetic resonance scanner; priority journal; white matter; anatomy and histology; brain; computer assisted diagnosis; diffusion weighted imaging; evaluation study; information processing; procedures; young adult; Adult; Brain; Datasets as Topic; Diffusion Magnetic Resonance Imaging; Diffusion Tensor Imaging; Female; Humans; Image Interpretation, Computer-Assisted; Male; White Matter; Young Adult |
顯示於: | 醫療器材與醫學影像研究所 |
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