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  4. Resolution of pathologic Q wave, left ventricular dysfunction and mitral regurgitation after dual coronary repair of the anomalous origin of the left coronary artery from the pulmonary artery
 
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Resolution of pathologic Q wave, left ventricular dysfunction and mitral regurgitation after dual coronary repair of the anomalous origin of the left coronary artery from the pulmonary artery

Journal
European Journal of Pediatrics
Journal Volume
167
Journal Issue
11
Pages
1277-1282
Date Issued
2008
Author(s)
Chiu H.-H.
JOU-KOU WANG  
CHUN-AN CHEN  
SHUENN-NAN CHIU  
MING-TAI LIN  
Lue H.-C.
CHUNG-I CHANG  
ING-SH CHIU  
MEI-HWAN WU  
DOI
10.1007/s00431-008-0667-4
URI
https://www.scopus.com/inward/record.uri?eid=2-s2.0-51849109124&doi=10.1007%2fs00431-008-0667-4&partnerID=40&md5=6e4c98edd7e9d71a337ea7562294466a
https://scholars.lib.ntu.edu.tw/handle/123456789/469631
Abstract
Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiac defect that usually presents as dilated cardiomyopathy in infancy. From 1984 to 2005, 13 (five males and eight females, 0.13%) out of 9,950 patients with congenital heart disease were identified as ALCAPA at our institute. Corrective surgery was performed at a median age of 9 months (range: 2 months to 5 years). Eleven patients underwent direct reimplantation of the left coronary artery (LCA) to the aorta, while two received extrapulmonary baffling. The overall survival rate was 92%. Only one patient died 5 months after reimplantation of the LCA due to acute myocardial ischaemia. Left ventricular ejection fraction (LVEF) was significantly lower in the eight (62%) patients operated during infancy than in those operated beyond 5 months (median: 35% vs. 75%). Left ventricle function was normalised in 11 patients (85%). Among the eight patients without concomitant mitral annuloplasty, mitral regurgitation (MR) improved to a mild or trivial degree in six patients and remained at the pre-operative level in two patients. Pathologic Q wave was noted in 11 patients, which eventually regressed in all except two cases. The median interval of recovery was 16 days, 6 months and 24 months for MR, LVEF and electrocardiogram (ECG) changes, respectively. In conclusion, ALCAPA is also a rare disease in Asian countries, such as Taiwan. The subsequent recovery of MR, left ventricular (LV) function and even pathologic Q wave can be expected after dual coronary repair, regardless of the age at repair. ? 2008 Springer-Verlag.
SDGs

[SDGs]SDG3

Other Subjects
anomalous origin of the left coronary artery from the pulmonary artery; article; Asian; child; clinical article; congenital heart malformation; controlled study; electrocardiogram; female; groups by age; heart left ventricle ejection fraction; heart left ventricle failure; heart left ventricle function; human; left coronary artery; male; mitral annuloplasty; mitral valve regurgitation; mortality; plastic surgery; preoperative period; priority journal; pulmonary artery; Q wave; reimplantation; survival; Taiwan; Child; Child, Preschool; Coronary Vessels; Echocardiography; Electrocardiography; Female; Follow-Up Studies; Humans; Infant; Long QT Syndrome; Male; Mitral Valve Insufficiency; Postoperative Complications; Preoperative Care; Pulmonary Artery; Severity of Illness Index; Ventricular Dysfunction, Left
Type
journal article

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