|Title:||Accuracy of biphasic response, sustained improvement and worsening during dobutamine echocardiography in predicting recovery of resting myocardial dysfunction after revascularization: Comparison with thallium-201 SPECT||Authors:||Huang P.-J.
|Issue Date:||2001||Journal Volume:||27||Journal Issue:||7||Start page/Pages:||925-931||Source:||Ultrasound in Medicine and Biology||Abstract:||
To evaluate the accuracy of various types of wall motion response during dobutamine echocardiography (DE) in predicting functional recovery after revascularization, we studied 30 patients with stable coronary disease and left ventricular dysfunction by simultaneous DE and 201Tl reinjection SPECT. Among 480 segments (16 segments/patient), 199 had abnormal wall motion at baseline and 167 were revascularized. The predictive value for recovery of function was 72% for a biphasic response, 61% for sustained improvement, 77% for worsening, and 27% for no change (p < 0.01 vs. each). Biphasic response had a sensitivity of 40% and specificity of 85%. Combining biphasic, sustained improvement and worsening responses, the sensitivity, specificity and accuracy were 76%, 65% and 71%, respectively. For 201Tl SPECT, they were 90%, 65% and 78%, respectively. Thus, a biphasic response alone is of low sensitivity. Combination of biphasic, sustained improvement and worsening responses gives an accuracy rate comparable to that of 201Tl reinjection SPECT in assessing functional recovery. ? 2001 World Federation for Ultrasound in Medicine & Biology.
|ISSN:||0301-5629||DOI:||10.1016/S0301-5629(01)00378-7||metadata.dc.subject.other:||Diseases; Patient treatment; Biphasic response; Echocardiography; dobutamine; thallium 201; accuracy; adult; aged; article; clinical article; comparative study; controlled study; coronary artery disease; disease course; disease severity; echocardiography; female; heart left ventricle failure; human; male; myocardial disease; priority journal; prognosis; revascularization; sensitivity and specificity; single photon emission computer tomography; treatment outcome; Adult; Aged; Coronary Disease; Dobutamine; Echocardiography; Female; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Revascularization; Predictive Value of Tests; Prognosis; Rest; Sensitivity and Specificity; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon; Ventricular Dysfunction, Left
|Appears in Collections:||醫學教育暨生醫倫理學科所|
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