https://scholars.lib.ntu.edu.tw/handle/123456789/469863
標題: | Ultrasonic tissue characterization in predicting residual ischemia and myocardial viability for patients with acute myocardial infarction | 作者: | Lin, Lung-Chun CHAU-CHUNG WU YI-LWUN HO MING-FONG CHEN Liau C.-S. Lee Y.-T. |
公開日期: | 1998 | 出版社: | Elsevier Sci Ltd, Exeter, United Kingdom | 卷: | 24 | 期: | 8 | 起(迄)頁: | 1107-1120 | 來源出版物: | Ultrasound in Medicine and Biology | 摘要: | The identification of viable myocardium and residual ischemia in patients with acute myocardial infarction has important prognostic implications. The ultrasonic tissue characterization with integrated backscatter and dobutamine-atropine stress echocardiography were performed 8.3 ± 3 days after AMI in 30 patients. After coronary angioplasty for the residual stenosis of infarct-related artery, both modalities were repeated. The parameter obtained from ultrasonic tissue characterization, phase- weighted variation, could differentiate the myocardium with residual coronary stenosis or nonviable myocardium from the viable myocardium without residual coronary stenosis (p < 0.001). Using the cutoff value of 5.8 dB, the sensitivity, specificity and accuracy for detecting viable myocardium without residual coronary stenosis were 75%, 100% and 90.2%, respectively. The phase- weighted variation of the viable infarction zone restored after the coronary stenosis was relieved. In contrast, the nonviable myocardium had a small phase-weighted variation that was irrelevant to the patency of the infarct- related artery. The ultrasonic tissue characterization may be used in identifying patients with acute myocardial infarction whose infarction zones are viable without residual ischemia.The identification of viable myocardium and residual ischemia in patients with acute myocardial infarction has important prognostic implications. The ultrasonic tissue characterization with integrated backscatter and dobutamine-atropine stress echocardiography were performed 8.3±3 days after AMI in 30 patients. After coronary angioplasty for the residual stenosis of infarct-related artery, both modalities were repeated. The parameter obtained from ultrasonic tissue characterization, phase-weighted variation, could differentiate the myocardium with residual coronary stenosis or nonviable myocardium from the viable myocardium without residual coronary stenosis (p<0.001). Using the cutoff value of 5.8 dB, the sensitivity, specificity and accuracy for detecting viable myocardium without residual coronary stenosis were 75%, 100% and 90.2%, respectively. The phase-weighted variation of the viable infarction zone restored after the coronary stenosis was relieved. In contrast, the nonviable myocardium had a small phase-weighted variation that was irrelevant to the patency of the infarct-related artery. The ultrasonic tissue characterization may be used in identifying patients with acute myocardial infarction whose infarction zones are viable without residual ischemia. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032191164&doi=10.1016%2fS0301-5629%2898%2900104-5&partnerID=40&md5=d04861a446f1e582ccebc9572e39571e https://scholars.lib.ntu.edu.tw/handle/123456789/469863 |
ISSN: | 0301-5629 | DOI: | 10.1016/S0301-5629(98)00104-5 | SDG/關鍵字: | Acoustic wave backscattering; Blood vessels; Cardiology; Medical imaging; Tissue; Angioplasty; Myocardial infarction; Echocardiography; atropine; dobutamine; acute heart infarction; adult; aged; artery diameter; article; cell viability; clinical article; coronary artery dilatation; coronary artery obstruction; female; heart left ventricle function; heart muscle ischemia; human; male; prediction; priority journal; prognosis; stress echocardiography; tissue characterization; Angioplasty; Atropine; Coronary Angiography; Coronary Disease; Dobutamine; Echocardiography; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Contraction; Myocardial Infarction; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Thrombolytic Therapy |
顯示於: | 醫學教育暨生醫倫理學科所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。